RPTP Bta Pure 12/RPTP Bta 150ug
货号：
610180 基本售价：
7961.0 元 规格：
150ug
产品信息
概述| 货号 | 610180 |
| 描述 | Receptor-typeprotein-tyrosinephosphataseβ(RPTPβ or PTP ζ ) is the first mammalian tyrosine phosphatase to be characterized whose expression is limited to the nervous system. RPTP β consists of a large extracellular domain, a single transmembrane domain, and a cytoplasmic portion with two tandem catalytic domains. Three forms of RPTP β exist which appear to be derived from alternative splicing. The 9.5 kb and 6.4 kb transcripts encode two transmembrane forms. The 8.5 kb transcript encodes a secreted form of the extracellular domain of RPTP β . A region of 266 amino acids in the extracellular domain shows a high degree of homology with carbonic anhydrase. This region is very similar to rat brain chondroitin sulfate proteoglycan (3F8 PG) which appears to be the rat homologue of the entire extracellular domain of human RPTP β . The apparent molecular weight of human RPTP β is 250 kDa and approaches 300 kDa when the protein is glycosylated. This antibody was generated against a region known to have a high degree of homology to other proteoglycans, such as RPTP γ (75% homology). |
| 别名 | PTPζ; Receptor-type Protein-Tyrosine Phosphatase β |
| 同种亚型 | IgG1 |
| 反应种属 | Human (QC Testing) Mouse, Rat (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC, IP, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human RPTPβ aa. 2098-2307 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
