ZRP-1 Pure 16/ZRP-1 150ug
货号:
612255 基本售价:
7885.0 元 规格:
150ug
产品信息
概述货号 | 612255 |
描述 | Zyxin is a zinc-binding metalloprotein found in focal adhesion plaques. It contains a proline-rich N-terminal domain and a C-terminal domain containing three LIM domains. LIM domains are characterized as zinc-binding motifs involved in gene expression and protein-protein interactions. Zyxin related protein 1 (ZRP-1) was identified through its interaction with the second PDZ domain of PTP1E. ZRP-1 has also been identified as Thyroid Receptor Interacting Protein-6 (TRIP6) during screening for binding partners of the thyroid hormone receptor. ZRP-1 contains an N-terminal proline-rich region (PRR), and three double zinc finger LIM domains in the C-terminal region. ZRP-1 mRNA has been reported to be widely expressed with strong expression in heart, placenta, lung, liver, kidney, and pancreas. ZRP-1 may interact with focal adhesions similar to other LIM domain proteins in the zyxin-related subfamily. However, ZRP-1 also contains nuclear export signal, and treatment of cells with leptomycin B leads to movement of ZRP-1 from the cytoplasm to the nucleus. Thus, ZRP-1 may be important for relaying signals from focal adhesions to the nucleus. |
别名 | Zyxin Related Protein-1; TRIP6; Thyroid Receptor Interacting Protein-6 |
同种亚型 | IgG1 |
反应种属 | Mouse (QC Testing) Human, Rat (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB |
性能供应商 | BD Pharmingen |
免疫原 | Human ZRP-1 aa. 103-209 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |