LR11 Pure 48/LR11 150ug
货号：
611861 基本售价：
7885.0 元 规格：
150ug
产品信息
概述| 货号 | 611861 |
| 描述 | The low-density lipoprotein receptor (LDLR) functions in lipoprotein transport pathways, and is involved in familial hypercholesterolemia. Homologues of the LDLR may have diverse functions and their ligands may include biological inactive plasma carrier complexes, plasma lipoproteins, yolk precursors, toxins, and extracellular lipoproteins. LR11 (also known as sorLA-1 and gp250) is a lipoprotein receptor homologue that contains 11 LDL receptor ligand binding repeats (LDLRs), 5 LDL receptor "YWTD"repeats, a large fibronectin-type III (FIII) hexarepeat domain similar to neural adhesion proteins, and a domain with similarity to the yeast receptor for vacuolar protein sorting (Vsp10p). LR11mRNA is expressed at high levels in brain, but is also found in liver, pancreas, adrenal gland, and testis. LR11 can bind the ER and Golgi localized receptor associated protein (RAP), which binds to many members of the LDLR family and prevents aggregation of ligands to the LDLRs. In addition, LR11 binds apolipoprotein E-containing lipoproteins. Thus, LR11 is a lipoprotein binding receptor that may have additional functions related to protein sorting and neuronal development. |
| 别名 | SorLA; gp250; Lipoprotein Receptor-11 |
| 同种亚型 | IgG2a |
| 反应种属 | Rat (QC Testing) Human, Mouse (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human LR11 aa. 1220-1337 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
