PCNA Pure 24/PCNA 150ug
货号:
610665 基本售价:
7885.0 元 规格:
150ug
产品信息
概述货号 | 610665 |
描述 | Progression of the mammalian cell cycle is regulated in two different ways: 1) phosphorylation and dephosphorylation of key proteins; 2) synthesis anddegradation of regulatory factors. The Proliferating Cell Nuclear Antigen (PCNA) was initially identified as a nuclear antigen in proliferating cells and was subsequently described as a subunit for DNA polymerase δ. Human PCNA is 262 amino acids with an apparent molecular weight of 36 kDa. PCNA protein levels peak during the S-phase of the cell cycle, at which time it forms a complex with the p21 inhibitor. PCNA is almost undetectable in other phases of the cycle. Because of its unique expression, PCNA has been extensively used in studies associating the prognosis of tumor progression and neoplastic proliferation. |
别名 | Proliferating Cell Nuclear Antigen |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Mouse, Rat, Dog (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IHC, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human PCNA aa. 68-230 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |