ROCK-II/ROK Alp Pure 21/ROCK-II 150ug
货号：
610624 基本售价：
7885.0 元 规格：
150ug
产品信息
概述| 货号 | 610624 |
| 描述 | Activity of the GTP-binding proteins is regulated by GAPs, that accelerate binding, and GTPases, that enhance the rate of GTP hydrolysis (Ras, Rho, cdc42Hs, and Rac). The isoforms of Rho, a small GTP-binding protein, regulate cellular processes such as the formation of the stress fibers, lamelipodia, and filopodia. ROK α(RhoA-bindingk inase) is a Ser/Thr protein kinase that interects with the GTP-binding form of RhoA. Like RhoA, ROK α localizes at the cellular margins and colocalizes with acti filaments. The ROKα gene encodes a protein of 1302 amino acids with homology to the human myotonic kinase. Although ROK α binds to GTP-RhoA, it is not yet clear whether this interaction induces the kinase activity of ROK α. |
| 别名 | ROKα |
| 同种亚型 | IgG1 |
| 反应种属 | Mouse (QC Testing) Human, Rat, Dog (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC, IP, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat ROKα aa. 567-718 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
