Nek2 Pure 20/Nek2 150ug
货号：
610594 基本售价：
7885.0 元 规格：
150ug
产品信息
概述| 货号 | 610594 |
| 描述 | Reversible protein phosphorylation is critical for progression through the cell cycle and mitosis. In Aspergillus nidulans, the nimagene (neverinmitosis) encodes a protein kinase that is essential for mitosis. Three human genes (nek1, 2, and3[Nima-relatedkinase]) with significant homology to the A. nidulans nima have been reported. The nek2gene encodes a protein of 445 amino acids and, like its fungal homolog, its expression is regulated throughout the cell cycle. In Hela cells, Nek2 activity and expression are low during M and G1 phases of the cell cycle. However, both parameters increase during S phase and mitosis. In addition, Nek2 phosphorylates protein substrates exclusively at serine and threonine residues. Thus, like its fungal homolog, Nek2 may be a crucial element in controlling the cells entry into S phase and mitosis. |
| 别名 | Nima Related Kinase 2 |
| 同种亚型 | IgG1 |
| 反应种属 | Human (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Nek2 aa. 244-444 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
