RIP Pure 38/RIP 150ug
货号:
610459 基本售价:
7885.0 元 规格:
150ug
产品信息
概述货号 | 610459 |
描述 | Binding or cross linking of the Fas antigen (also known as APO-1 and CD95) is known to elicit apoptosis in susceptible cells. Fas is a member of a family of cell surface receptors which includes tumor necrosis factor receptors (TNF-R, and TNF-R2) and nerve growth factor receptors (NGF-R), CD40, OX40, CD30, CD27, and 4-1BB. Several members of this family have been shown to regulate or induce cell death (TNF-R1 and TNF-R2). A 74 kDa member of this family protein named RIP (Receptor Interacting Protein) contains an N-terminal region with homology to protein kinases and a C-terminal region containing a cytoplasmic "death domain" present in both Fas and TNF-R1. Both Fas and RIP have been shown to require this death domain to induce apoptosis and overexpression of RIP has been shown to induce cell death in transfected cells. |
别名 | Receptor Interacting Protein |
同种亚型 | IgG2a |
反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IP, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human RIP aa. 385-650 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |