LAR Pure 7/LAR 150ug
货号：
610351 基本售价：
7885.0 元 规格：
150ug
产品信息
概述| 货号 | 610351 |
| 描述 | The Leukocyte common Antigen-Related (LAR) receptor protein tyrosine phosphatase (RPTP) is one of approximately 20 known, distinct transmembrane RPTPs. LAR consists of an extracellular region with three Ig-like and eight fibronectin type III-like (FNIII) domains and a cytoplasmic region containing two tyrosine phosphatase domains typical of RPTPs. The Ig and FNIII domains of LAR show some sequence similarity to domains in the neural cell adhesion molecule N-CAM, a neural surface glycoprotein which mediates cell adhesion and neurite outgrowth. Studies suggest that LAR regulates neurite outgrowth and pathfinding during neural development. N-CAM and other cell adhesion molecules that affect neurite outgrowth, such as L1, TAG-1, and fasciculin II, lack intrinsic kinase or phosphatase activity. Thus, LAR is part of a distinct class of proteins with both cell adhesion and tyrosine phosphatase functions. LAR transcripts are alternatively spliced and that splicing is regulated during development. It is postulated that the various spliced forms of LAR each have specialized functions in the nervous system and play a role in neural development and regeneration. |
| 别名 | Leukocyte common Antigen-Related |
| 同种亚型 | IgG2a |
| 反应种属 | Human (QC Testing) Mouse, Rat (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human LAR aa. 24-196 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
