Gma-Catenin Pure 15/Gma-Catenin150ug
货号：
610254 基本售价：
7885.0 元 规格：
150ug
产品信息
概述| 货号 | 610254 |
| 描述 | γ -Catenin (plakoglobin) was identified as a compenent of desmosomes where it associates with desmoglein. γ -Catenin and β -Catenin are closely related proteins that have significant homology with the Drosophila armadillo protein. In addition to complexing with E-Cadherin, γ -Catenin and β -Catenin have been observed in association with the intracellular domain of N-Cadherin. It has been proposed that one molecule of α -Catenin and at least one molecule of β -Catenin and γ -Catenin simultaneously bind to a single cadherin molecule. A 19 amino acid sequence of desmoglein (Dsg1) was found to be critical for binding of γ -Catenin. This region has significant homology to the catenin-binding domain of classical cadherins, thus suggesting a common mechanism for γ -Catenin localization at both adherens junctions and desmosomes. |
| 同种亚型 | IgG2a |
| 反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IP, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human γ-Catenin aa. 553-738 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
