Connexin-43 Pure 2/Connexin-43 150ug
货号:
610062 基本售价:
7885.0 元 规格:
150ug
产品信息
概述货号 | 610062 |
描述 | Gap junctions are intercellular protein pores. They enable cell-to-cell communication by allowing passage of ions and other small molecules. The subunits of gap junction channels are assembled from a family of proteins called connexins. Individual connexin molecules join to make hexameric hemichannels termed connexons; these structures dock to connexons on neighboring cells, forming gap junction pores. Connexin-43 is a member of the connexin family possessing four transmembrane regions, with cytoplasmic amino and carboxyl terminals. It undergoes rapid turnover in the cell and its monomers may reside in the ER/Golgi network, forming a reservoir available for assembly upon degradation of existing connexin-43 channels. In addition, it is believed that phosphorylation of connexin-43 plays a regulatory role both in the assembly of connexons and in gating activity at the gap junction. |
同种亚型 | IgG1 |
反应种属 | Rat (QC Testing) Human, Mouse, Dog, Chicken (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IF |
性能供应商 | BD Pharmingen |
免疫原 | Rat Connexin-43 aa. 252-270 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |