TRADD Pure 37/TRADD 150ug
货号:
610573 基本售价:
7771.0 元 规格:
150ug
产品信息
概述货号 | 610573 |
描述 | TNFα (Tumor Necrosis Factor) stimulates programmed cell death and NF-κB activation as a result of its binding to the TNF receptor 1 (TNFR1). Within this receptor, a sequence referred to as the “death domain” has been shown to be necessary for both of these functions. Using the yeast two-hybrid system to detect proteins which interact with the receptor through this “death domain”, a 34 kDa protein was found and designated TRADD (TNFR1-Associated Death Domain protein). TRADD appears to contain no intrinsic catalytic activity. It also contains a death domain and it has been shown to bind to FADD and RIP. Mutational analysis of TRADD demonstrates that programmed cell death and NF-κB activation are distinct and controlled independently. |
别名 | TNFR1-Associated Death Domain protein |
同种亚型 | IgG1 |
反应种属 | Human (QC Testing) Rat (Tested in Development) |
来源宿主 | Mouse |
使用方法 | WB, IHC, IP, IF |
性能供应商 | BD Pharmingen |
免疫原 | Human TRADD aa. 163-312 |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
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存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
浓度 | 250 µg/ml |