PKA RI Pure 18/PKA [RI] 150ug
货号：
610166 基本售价：
7771.0 元 规格：
150ug
产品信息
概述| 货号 | 610166 |
| 描述 | cAMP-dependent Protein Kinase (PKA) is composed of two distinct subunits: catalytic (C) and regulatory (R). Four regulatory subunits have been identified: RI α , RIß, RII α , and RIIß. These subunits define type I and II cAMP-dependent protein kinases. Following binding of cAMP, the regulatory subunits dissociate from the catalytic subunits, rendering the enzyme active. Type I and type II holoenzymes have three potential C subunits (C α , Cß, or C γ ). Type II PKA can be distinguished by autophosphorylation of the R-subunits, while type I PKA binds Mg/ATP with high affinity. Most cells express both type I and type II PKAs. Although the R α isoforms are ubiquitously expressed, the Rß isoforms are predominant in nervous and adipose tissues. The levels of expression of the different subunits vary according to cell and tissue type. |
| 同种亚型 | IgG2b |
| 反应种属 | Human (QC Testing) Mouse, Rat, Dog, Chicken, Frog (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IP, IF, Bioimg |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse PKA [RI] subunit aa. 225-381 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
