CXCR7 BV421 10D1 100ug
货号：
566233 基本售价：
7020.0 元 规格：
100ug
产品信息
概述| 货号 | 566233 |
| 描述 | The 10D1 monoclonal antibody specifically binds to mouse and human C-X-C chemokine receptor type 7 (CXCR7), a G protein-coupled receptor that interacts with high affinity to SDF-1 (CXCL12) and with low affinity to CXCL11 (I-TAC). These chemokines also bind to CD184 (CXCR4) and CD183 (CXCR3), respectively, and induce functional processes such as calcium mobilization and cell migration. In contrast to CXCR4, CXCR7-dependent signaling outcomes are somewhat unclear and may vary with cell type. CXCR7 is involved in the alignment of marginal-zone B lymphocytes to the splenic marginal zone and also plays critical roles in embryogenesis and malignancies. |
| 别名 | ACKR3, CMKOR, RDC1, GPR159 |
| 同种亚型 | Mouse C57BL/6 IgG2a, κ |
| 反应种属 | Mouse (QC Testing) Human (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human CXCR7 Transfected Cell Line |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
