Noggin Pure L98-788 100ug
货号:
560170 基本售价:
5900.0 元 规格:
100ug
产品信息
概述货号 | 560170 |
描述 | The L98-788 monoclonal antibody reacts with noggin glycoprotein, a secreted antagonist of the bone morphogenic proteins (BMPs). Noggin homodimers block the binding of BMPs to their receptors. The phenotypes of natural noggin mutations in humans (such as symphalangism proximal syndrome, synostoses syndrome 1, and brachydactyly type B2) and noggin-null mice indicate that noggin regulates cartilage and joint formation. Noggin is also involved in neural tube, somite, and myocardial morphogenesis and osteoblastic/osteoclastic responses to metastatic cancers. Noggin is highly conserved in vertebrates; the amino-acid sequence identities of human noggin with mouse, rat, bovine, equine, chicken, and frog (Xenopus) noggin are 99%, 99%, 98%, 97%, 89%, and 81%, respectively. |
同种亚型 | IgG1,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | WB |
性能供应商 | BD Pharmingen |
免疫原 | Human Noggin Recombinant Protein |
存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |