货号 | FAB5264U-100UG |
别名 | HHV8ORF74; HHV8-ORF74; KSHV-vGPCR | 全称 | Human Herpesvirus 8 ORF74 |
应用 | Flow Cytometry |
目标/特异性 | Detects viral HHV8-ORF74. |
使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 4961460 (Viral) |
免疫原 | NS0 mouse myeloma cell line transfected with viral HHV8-ORF74 Met1-Thr342 Accession # AAB51506 |
生物活性 | Viral |
标记 | Alexa Fluor 350 |
背景 | HHV8‑ORF74 is a 342 amino acid viral 7-transmembrane receptor encoded by the Kaposis sarcoma-associated herpesvirus 8. The G‑protein-coupled receptor is a constitutively active homologue of CXCR2, the CXCL8 receptor (IL-8 RB). It contributes to Kaposis sarcoma by triggering expression of paracrine factors such as VEGF-A, inflammatory cytokines, adhesion molecules and chemokines, and enhancing cell growth. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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