ROR2 Pure Ror2 100ug
货号：
565550 基本售价：
5500.0 元 规格：
100ug
产品信息
概述| 货号 | 565550 |
| 描述 | The Ror2 monoclonal antibody specifically binds to the ST2 intracellular domain of ROR2 (Receptor tyrosine kinase-like Orphan Receptor 2). ROR2 is a type I transmembrane protein that belongs to a small family of receptor tyrosine kinases containing frizzled domains. Based on the homology of ROR2 and Wnt receptors Frz domains, ROR2 has been linked to Wnt signaling and embryonic development. Wnt5a-ROR2 signaling promotes osteoclastogenesis, and ROR2 is also critical for the formation of skeleton, heart, and genitals. In normal adult tissues, ROR2 is expressed in very low levels or undetectable. There is mounting evidence that ROR2 expression is associated with either tumor progression or suppression in different tissues. In humans, mutations in the ROR2 gene are associated with the autosomal recessive form of Robinow Syndrome and autosomal dominant Brachydactyly type B. |
| 别名 | Neurotrophic tyrosine kinase, receptor-related 2; NTRKR2, BDB, BDB1 |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Human (QC Testing) Rat (Tested in Development) Mouse (Reported) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse ROR2 Peptide |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
