Nucleostemin Pure P22-1125 100ug
货号：
562749 基本售价：
5500.0 元 规格：
100ug
产品信息
概述| 货号 | 562749 |
| 描述 | Nucleostemin, also known as guanine nucleotide binding protein-like 3 (GNL3), was first identified in CNS stem cells and has subsequently been shown to be expressed in embryonic stem cells, bone-marrow derived stem cells, corneal epithelial cells, as well as multiple cancer cell lines and tumors. As its name suggests, nucleostemin is localized to the nucleolus and contains GTP-binding motifs. Nucleostemin has been implicated in cell cycle progression and the maintenance of proliferation. Interestingly, the depletion and the over-expression of nucleostemin cause cell cycle arrest. Both these mechanisms of cell cycle arrest are through a p53 dependant manner. The expression of nucleostemin is down-regulated during stem cell differentiation in vivo and in vitro. |
| 别名 | GNL3, E2-induced gene 3 protein, NNP47, Nucleolar GTP-binding protein 3 |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Human (QC Testing) Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Nucleostemin Recombinant Protein |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
