GAD65 Pure GAD-6 100ug
货号：
559931 基本售价：
5377.0 元 规格：
100ug
产品信息
概述| 货号 | 559931 |
| 描述 | γ -aminobutyric acid (GABA) is an amino acid neurotransmitter that is considered to be the major inhibitory neurotransmitter in the mammalian central nervous system. The highest concentrations of GABA are found in the brain, where it is synthesized from glutamic acid to GABA by an enzyme called glutamic acid decarboxylase (GAD). GAD is also expressed in the insulin-producing β cells of the islets of Langerhans. Two isoforms of GAD are present in rat brain, GAD65 and GAD67, based on their relative molecular weight in kDa. Both isoforms have significant levels of homology in the catalytic portion of the molecule, but differ greatly in the first 95 amino acids in the N-terminal region. GAD65 migrates at ~65 kDa in SDS/PAGE. The antibody is reported to recognize rat, human, mouse, and pig GAD65. Purified GAD65 from rat brain was used as the immunogen. The specific epitope recognized by this clone is a linear epitope localized in the last 41 amino acids of GAD65. |
| 别名 | Glutamic acid decarboxylase |
| 同种亚型 | IgG2a,κ |
| 反应种属 | Rat (QC Testing) Human, Mouse, Pig (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC(Fr), IP |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Purified Rat GAD65 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
