SSEA-1 Pure MC480 100ug
货号：
560079 基本售价：
5282.0 元 规格：
100ug
产品信息
概述| 货号 | 560079 |
| 描述 | The MC480 monoclonal antibody reacts with Stage-SpecificEmbryonicA ntigen-1 (SSEA-1), which is a terminal carbohydrate epitope (3-fucosyl-N-acetyllactosamine or 3-FAL) on glycoproteins and lactose series glycolipids. SSEA-1 is related to Lewis blood group antigens and is found in a variety of embryonic and adult tissues and cancers. As its name implies, the expression of SSEA-1 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. However, its expression pattern differs in the human and mouse. In the human, SSEA-1 is not found on embryonic stem (ES) cells, embryonic inner cell mass (ICM), or teratocarcinoma (embryonal carcinoma or EC) cells. As human EC and ES cells undergo differentiation, SSEA-1 expression is upregulated. In the adult, the same epitope is expressed as CD15 on granulocytes and monocytes, but not lymphocytes or dendritic cells. In the mouse, SSEA-1 is found on EC, ES, and primordial germ cells, 8-cell to blastocyst embryos, ICM, and on subpopulations of cells in the adult central nervous system, including stem cells. In contrast to the human, SSEA-1 expression is reduced as mouse EC and ES cells undergo differentiation. |
| 别名 | 3-FAL, X-hapten, LeX antigen, CD15 |
| 同种亚型 | IgM,κ |
| 反应种属 | Human, Mouse (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB, Bioimg |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Teratocarcinoma Cell Line |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
