DFF40/CAD Pure Poly 1260 50ug
货号:
550603 基本售价:
5122.0 元 规格:
50ug
产品信息
概述货号 | 550603 |
描述 | The DNA fragmentation factor (DFF) is a complex composed of two subunits, DFF40/CAD and DFF45. DFF40/CAD is the nuclease responsible for DNA fragmentation during apoptosis. DFF45 is a molecular chaperone that inhibits the activity of DFF40/CAD. During apoptosis, activated caspase-3 cleaves DFF45 (45 kDa) into 30 and 11 kDa fragments, resulting in the release and activation of DFF40. Activated DFF40 causes DNA fragmentation which has long been considered to be a hallmark of apoptotic cell death. DFF40 migrates at approximately 40 kDa in SDS/PAGE. The antibodies recognize human, mouse, and rat DFF40/CAD. A peptide corresponding to amino acids (a.a.) 203 to 218 of human DFF40 was used as the immunogen. |
同种亚型 | Ig |
反应种属 | Human (QC Testing) Mouse, Rat (Reported) |
来源宿主 | Rabbit |
使用方法 | WB |
性能供应商 | BD Pharmingen |
存放说明 | Store undiluted at 4°C.The polyclonal antibody was purified from antiserum by affinity chromatography.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |