GLUCAGON BV421 U16-850 50UG
货号：
565891 基本售价：
4950.0 元 规格：
50ug
产品信息
概述| 货号 | 565891 |
| 描述 | The U16-850 monoclonal antibody specifically binds to glucagon, a member of the secretin family of active peptides. Glucagon is an evolutionarily conserved peptide hormone that participates in the regulation of carbohydrate metabolism by counteracting the effects of insulin. Glucagon is produced by α cells in the islets of Langerhans of the pancreas. The CGC gene encodes the precursor molecule preproglucagon, which is cleaved to form proglucagon that is in turn cleaved to form at least four distinct peptides, including glucagon, in different tissues. Hypoglycemia causes the secretion of glucagon, which binds to the class B G-protein-coupled glucagon re ceptor that is mainly expressed in liver and kidney, causing reduced glycogenesis and glycolysis and increased glycogenolysis and gluconeogenesis. The expression of glucagon can be used to monitor the pancreatic differentiation of pluripotent stem cells. |
| 别名 | GLP1; GLP2; GRPP; GCG |
| 同种亚型 | Mouse BALB/c IgG1, κ |
| 反应种属 | Human (QC Testing) Rat, Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human glucagon Recombinant Protein |
| 标记 | BV421 |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon™ BV421 under optimum conditions, and unconjugated antibody and free BD Horizon™ BV421 were removed.
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| 存储溶液 | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
