Paxillin TRITC 349 50ug
货号：
610055 基本售价：
4761.0 元 规格：
50ug
产品信息
概述| 货号 | 610055 |
| 描述 | A number of cytoskeletal proteins are tyrosine phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts. One of these is the 68 kDa paxillin protein. Paxillin is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers. It is also present in the focal adhesions of Madin-Darby canine kidney epithelial cells, but is absent from the cell adherens junctions of these cells. Paxillin purified from chicken gizzard migrates as a diffuse band on SDS-PAGE with molecular weight of 65-70 kDa. It binds to the rod domain of vinculin, another focal adhesion protein. It is thought that phosphorylation of paxillin may have a role in that disassembly of focal adhesions and stress fibers during transformation. |
| 同种亚型 | IgG1 |
| 反应种属 | Mouse (QC Testing) Human (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Chicken Paxillin aa. 1-557 |
| 标记 | TRITC |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with TRITC under optimum conditions, and unreacted TRITC was removed.Store undiluted at -20°C.
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| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
