| 货号 | FAB6676V-100UG |
| 别名 | CD4 antigen (p55); CD4 antigen; CD4 molecule; CD4 receptor; CD4; CD4mut; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4 |
| 应用 | Flow Cytometry |
| 目标/特异性 | Detects cotton rat CD4 in direct ELISAs.In direct ELISAs, no cross-reactivitywith recombinant CD4 from human, mouse, rat, cat, or dog is observed. |
| 使用方法 | Flow Cytometry: 0.25-1 µg/106cells |
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 920 (Human); 12504 (Mouse); 24932 (Rat); 403931 (Canine); 493775 (Feline) |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant cotton rat CD4 Lys26-Pro393 |
| 生物活性 | Cotton Rat |
| 标记 | Alexa Fluor 405 |
| 背景 | CD4 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and the Th1, Th2, Th17, Tfh, and Treg subsets of mature T lymphocytes. In human, CD4 is additionally expressed on macrophages, neutrophils, monocytes, NK cells, and neurons and glial cells in the brain. CD4 binding to MHC class II molecules on antigen presenting cells contributes to the formation of the immunological synapse. CD4 also functions as a chemotactic receptor for IL-16 and, in human, as a coreceptor for the gp120 surface glycoprotein of HIV-1. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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