Myosin Vb/Myr 6 Pure 18/Myr 6 50ug
货号：
611608 基本售价：
4140.0 元 规格：
50ug
产品信息
概述| 货号 | 611608 |
| 描述 | Myosins are proteins that form oligomers consisting of two heavy chains and varying numbers of light chains. Many classes of myosin superfamily proteins which have similar N-terminal motor domains but divergent C-terminal domains have been characterized. Class V myosins interact via their C-terminal tails with specific proteins involved in organelle transport. In vertebrates, the myosin V family includes mouse myosin Va (dilute myosin) and Vb, rat myosin Vb ( my osin from rat6 ; myr 6), and chicken p190. Myr 6 includes an N-terminal globular domain, six IQ motifs in the neck region, two coiled-coil domains on each side (cc) of a PEST calpain cleavage region, and a C-terminal tail that is homologous to dilute myosin, AF-6, and GAD. Myr 6 is expressed highly in mouse heart, kidney, testis, liver, and lung. In rat brain, it is expressed highly in dentate gyrus,medial mamillary nuclei, amygdala, and choroid plexus. The tail region of myr 6 interacts with the C-terminal domain of BERP, a RING-B-box-coiled-coil protein that has been implicated in PC12 cell neurite outgrowth. Thus, myr 6 may function in the transport of organelles in a variety of neural and non-neuronal tissues. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat Myr6 aa. 940-1051 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
