Dystrobrevin Pure 23/Dystrobrevin 50ug
货号：
610766 基本售价：
4140.0 元 规格：
50ug
产品信息
概述| 货号 | 610766 |
| 描述 | Acetylcholine receptor clustering is considered an early event and a marker for synaptogenesis between a motor neuron and a muscle fiber. This process is mediated by the extracellular protein Agrin which binds to αandβ Dystroglycan, previously discovered as Dystrobrevin- associated proteins. Dystrobrevin binds to the actin cytoskeleton by its N-terminal domain, thus providing the link between the actin cytoskeleton and receptor clustering. In Torpedo electric organ, Dystrobrevin is a prominent phosphotyrosine-containing protein. Murine Dystrobrevins comprise a family of four related proteins (1-4) with similar function, generated by alternative splicing. Dystrobrevin-1 is 688 amino acids and has an apparent mobility of 87kDa. Dystrobrevin-2 shares almost identical sequence with Dystrobrevin-1 in the first 500 amino acids and has an apparent mobility of 59kDa. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) Mouse, Rabbit (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Dystrobrevin aa. 249-403 |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at -20°C.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
