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货号： bs-9037R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9037R-HRP
- 英文名称
- Anti-PDZK3/HRP
- 中文名称
- 辣根过氧化物酶标记的前列腺癌激活蛋白抗体
- 别 名
- Activated in prostate cancer protein; AIPC; KIAA0300; Likely ortholog of rat plakophilin related armadillo repeat protein interacting PDZ protein antibody PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain containing protein 2; PDZ domain containing protein 3; PDZD2; PDZK 2; PDZK2; PDZK-2; PDZK 3; PDZK3; PDZK-3; PIN1; Plakophilin related armadillo repeat protein interacting PDZ protein like; Rat plakophilin related armadillo repeat protein interacting PDZ protein like; PDZD2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse,
- 产品应用
- ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 310kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PDZK3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. PDZK3 contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, the PDZK3 gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.
Subunit:
Interacts with SCN10A, CTNND2 and PKP4 (By similarity).
Subcellular Location:
Cytoplasmic, Endoplasmic reticulum, Nuclear and Secreted
Tissue Specificity:
Isoform 2 is expressed (at protein level) in prostate and many prostate tumors.
Post-translational modifications:
A secreted form is produced by caspase-mediated proteolytic cleavage (By similarity).
Similarity:
Contains 6 PDZ (DHR) domains.
Database links:Entrez Gene: 23037Human
Entrez Gene: 68070Mouse
Entrez Gene: 65034Rat
Omim: 610697Human
SwissProt: O15018Human
SwissProt: Q9QZR8Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.