L-Caldesmon Pure 8/L-Caldesmon 50ug
货号：
610660 基本售价：
3726.0 元 规格：
50ug
产品信息
概述| 货号 | 610660 |
| 描述 | Caldesmon is a protein component of the thin filaments of smooth muscle myofibrils. It is also localized in the stress fibers of fibroblasts. Caldesmon was identified as a Ca2+/Calmodulin-binding protein with molecular weight of 120-150 kDa (H-Caldesmon) and 70-80 kDa (L-Caldesmon). H-Caldesmon is the primary isoform in smooth muscle while L-Caldesmon is most abundant in non-muscle cells. Caldesmon is capable of binding two calmodulin molecules, one at either end of the protein. Additionally, Caldesmon is an actin, myosin, and tropomyosin-binding protein. Human L-Caldesmon is a protein of 538 amino acids with mobility of 80 kDa. In vitro , L-Caldesmon inhibits the actomyosin ATPase in an F-Actin-dependent manner. L-Caldesmon may play an important function in motile processes such as secretion and organelle movement. |
| 别名 | CALD1; CDM |
| 同种亚型 | IgG1 |
| 反应种属 | Human (QC Testing) Mouse, Rat (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IF |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human L-Caldesmon aa. 251-395 |
| 存放说明 | Store undiluted at -20°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. |
| 浓度 | 250 µg/ml |
