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货号： bs-0791R 基本售价： 380.0 元 规格： 20ul
- 规格：20ul
- 价格：380.00元
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-0791R
- 英文名称
- CGRP
- 中文名称
- 降钙素基因相关肽2抗体
- 别 名
- CGRP-I + CGRP-II; CGRP-1/2; Procalcitonin; Beta type CGRP; CALC2; CALCB; Calcitonin 1; Calcitonin 2; Calcitonin gene related peptide; Calcitonin gene related peptide II; Calcitonin related polypeptide beta; CGRP; CGRP II; CGRP2; CT; Calcitonin/calcitonin related polypeptide alpha; Katacalcin; MGC126648; CALCA_HUMAN; CALCB_HUMAN; Calcitonin gene-related peptide 2; Beta-type CGRP; Beta-CGRP; Calcitonin gene-related peptide II; CGRP-II; CGRP-I.
- Specific References (5) | bs-0791R has been referenced in 5 publications.[IF=2.94] Tu, Guihua, et al. "P2X< sub>7 inhibition in stellate ganglia prevents the increased sympathoexcitatory reflex via sensory-sympathetic coupling induced by myocardial ischemic injury." Brain research bulletin (2013). Rat.PubMed:23688519[IF=2.63] Liu, Jun, et al. "Sensory–sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor." Purinergic Signalling (2013): 1-17. Rat.PubMed:23754120[IF=0.78] Liu, Zhi-ming, et al. "Mutual Effect between Neuropeptides and Inflammatory Cytokines in Neurogenic SMSCs of Human Temporomandibular Joint." J Huazhong Univ Sci Technol [Med Sci] 34.4 (2014): 602-607. WB ; Human.PubMed:25135735[IF=0.18] Wang, Jianlong, et al. "Basic fibroblast growth factor attenuates the degeneration of injured spinal cord motor endplates." Neural Regeneration Research 8.24 (2013): 2213. IHC-P ; Rat.PubMed:25206531[IF=5.23] He, Qin-Qin, et al. "MicroRNA-127 targeting of mitoNEET inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection." Scientific Reports 6 (2016). IHC-P ; Rat.PubMed:27748416
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 细胞生物 免疫学 神经生物学 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 3.8kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CGRP:65-130/130
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Function:
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
Subcellular Location:
Secreted.
Similarity:
Belongs to the calcitonin family.
SWISS:
P01256
Gene ID:
796
797
Database links:Entrez Gene: 796 Human
Entrez Gene: 797 Human
Entrez Gene: 116903 Mouse
Entrez Gene: 12310 Mouse
Entrez Gene: 171519 Rat
Entrez Gene: 24241 Rat
Omim: 114130 Human
Omim: 114160 Human
SwissProt: P01258 Human
SwissProt: P06881 Human
SwissProt: P10092 Human
SwissProt: P70160 Mouse
SwissProt: Q99JA0 Mouse
SwissProt: P01256 Rat
SwissProt: P01257 Rat
Unigene: 37058 Human
Unigene: 534305 Human
Unigene: 273838 Mouse
Unigene: 4361 Mouse
Unigene: 88080 Rat
Unigene: 90085 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CGRP活性多肽，有37个氨基酸组成，具有多种生理功能，其药理作用已受到广泛重视.
CGRP （又称CGRP-1/2或CGRPa/β）广泛分布于神经系统的一种神经肽，在外周及脊髓参与伤害性信息的传递及痛敏化的形成，并与P物质、兴奋性氨基酸、辣椒素1型受体、趋化因子、激活素、大麻素受体、阿片受体、神经生长因子、血管活性肠肽、5-羟色胺、糖皮质激素等生物活性物质或受体在痛觉调制过程中存在相互影响。
- 产品图片
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CGRP) Polyclonal Antibody, Unconjugated (bs-0791R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Tissue/cell: human endometrium carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-CGRP/CGRP2 Polyclonal Antibody, Unconjugated(bs-0791R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining