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货号： bs-9762R-PE 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9762R-PE
- 英文名称
- Anti-FGF18/PE
- 中文名称
- PE标记的成纤维细胞生长因子18抗体
- 别 名
- FGF 18; FGF18; FGF-18; Fibroblast Growth Factor 18; ZFGF5; FGF18_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞凋亡 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Cow, Rabbit, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 21kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FGF18
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
Function:
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.
Subunit:
Interacts with FGFR3 and FGFR4.
Subcellular Location:
Secreted
Similarity:
Belongs to the heparin-binding growth factors family.
Database links:Entrez Gene: 8817 Human
Entrez Gene: 14172 Mouse
Entrez Gene: 29369 Rat
Omim: 603726 Human
SwissProt: Q0VCA0 Cow
SwissProt: O76093 Human
SwissProt: O89101 Mouse
SwissProt: O88182 Rat
Unigene: 87191 Human
Unigene: 339812 Mouse
Unigene: 44478 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.