货号 | FAB5449A |
别名 | CD44 antigen; CD44 molecule (Indian blood group); CD44; CD44R; CDw44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; Hyaluronate receptor; IN; LHR; MC56; MDU2; MDU2CD44 antigen (homing function and Indian blood group system); MDU3; MDU3CDW44; MIC4; MIC4MGC10468; MUTCH-I; Pgp1; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I |
反应种属 | Canine |
应用 | Flow Cytometry(10 µL/106cells) |
目标/特异性 | Detects canine CD44. |
使用方法 | Flow Cytometry: 10 µL/106cells |
来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 960 (Human); 12505 (Mouse); 25406 (Rat); 100126860 (Porcine) |
纯化方式 | Protein A or G purified from hybridoma culture supernatant |
免疫原 | Canine marrow cells Accession # Q28284 |
生物活性 | Canine |
标记 | Allophycocyanin |
背景 | Canine CD44 (also known as HCAM and Hermes) is a ubiquitously expressed 85‑90 kDa type I transmembrane glycoprotein that binds to hyaluronan, laminin, fibronectin, selectins, osteopontin, and chondroitin sulfate, and is involved in matrix adhesion, lymphocyte activation, and lymph node homing. The CD44 protein is expressed as a family of molecular isoforms that, in human and presumably in canine, are generated by alternative splicing and variable posttranslational modification. It is reported to form a complex with CD147. Within the N‑terminal invariant portion of the ECD (aa 14‑191), canine CD44 shares 90%, 83%, and 82% identity with human, mouse, and rat CD44, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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Detection of CD44 in Canine Blood-Derived Lymphocytes by Flow Cytometry. Canine blood-derived lymphocytes were stained with Mouse Anti-Canine CD44 APC‑conjugated Monoclonal Antibody (Catalog # FAB5449A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins. |