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货号： bs-9892R-PE 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9892R-PE
- 英文名称
- Anti-CAP57/PE
- 中文名称
- PE标记的中性粒细胞杀菌蛋白BP30抗体
- 别 名
- Neutrophil Bactericidal Protein BP30; Bactericidal permeability-increasing protein; Bactericidal/permeability increasing protein; BPI; BPI_HUMAN; CAP 57; CAP-57; CAP57.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CAP57
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Function:
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Subunit:
Monomer. Homodimer; disulfide-linked.
Subcellular Location:
Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Tissue Specificity:
Restricted to cells of the myeloid series.
Similarity:
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
Database links:Entrez Gene: 671 Human
Omim: 109195 Human
SwissProt: P17213 Human
Unigene: 529019 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.