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货号： bs-20145R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20145R-Cy7
- 英文名称
- Anti-ZNF703/Cy7
- 中文名称
- Cy7标记的锌指蛋白703抗体
- 别 名
- FLJ14299; ZEPPO1; Zinc finger elbow-related proline domain protein 1; Zinc finger protein 703; ZN703_HUMAN; ZNF503L; znf703; ZPO1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF703
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.
Subcellular Location:
Nucleus. Cytoplasm
Tissue Specificity:
Expressed in mammary epithelium.
DISEASE:
Amplification of the gene correlates with its protein expression in tumor cells. ZNF703 is a classical breast cancer oncogene since it is able to transform non-malignant cells and increase cellular proliferation.
Similarity:
Belongs to the Elbow/Noc family.
Contains 1 C2H2-type zinc finger.
Database links:Entrez Gene: 80139Human
Entrez Gene: 353310Mouse
Entrez Gene: 680717Rat
SwissProt: Q9H7S9Human
SwissProt: P0CL69Mouse
Unigene: 726062Human
Unigene: 212469Mouse
Unigene: 15384Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.