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货号： bs-9610R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9610R-HRP
- 英文名称
- Anti-MYH9/HRP
- 中文名称
- 辣根过氧化物酶标记的肌球蛋白重链9抗体
- 别 名
- non-muscle Myosin IIA; Myosin heavy polypeptide 9 non muscle; Myosin-9; Myosin9; Myosin 9; Alternative namesnon-muscle IIa; type A; Cellular myosin heavy chain; Cellular myosin heavy chain type A; DFNA 17; DFNA17; EPSTS; FTNS; MHA; MYH 2A; MYH 9; MYH9; MYH9_HUMAN; MYHas8; MYHas8; MyHC 2A; MyHC-Iia; MyHC-Iia; MYHSA 2; MYHSA2; MYHSA2; Myosin 9; Myosin heavy chain 9; Myosin heavy chain 9 non muscle; Myosin heavy chain; Myosin heavy chain non muscle Iia; Myosin heavy chain nonmuscle Iia; myosin heavy polypeptide 2; NMHC II A; NMMHC A;NMMHC II a; NMMHC II-a; NMMHC IIA; NMMHC-A; NMMHC-IIA; NMMHCA; Non muscle myosin heavy chain A; Non muscle myosin heavy chain;Non muscle myosin heavy chain II A; Non muscle myosin heavy polypeptide 9; Non-muscle myosin heavy chain A; Non-muscle myosin heavy chain IIa; Nonmuscle myosin heavy chain A.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞外基质
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 226kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MYH9
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.Defects in MYH9 are the cause of May-Hegglin anomaly (MHA) . MHA is an autosomal dominant macrothrombocytopenia characterized by thrombocytopenia, giant platelets and leukokyte inclusions appearing as highly parallel paracrystalline bodies.
Function:
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.
Subunit:
Interacts with PDLIM2. Interacts with SLC6A4. Myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with RASIP1. Interacts with DDR1. Interacts with SVIL and HTRA3.
Subcellular Location:
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Tissue Specificity:
In the kidney, expressed in the glomeruli. Also expressed in leukocytes.
Post-translational modifications:
ISGylated.
Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.
Database links:Entrez Gene: 4627 Human
Entrez Gene: 17886 Mouse
Entrez Gene: 25745 Rat
Omim: 160775 Human
SwissProt: P35579 Human
SwissProt: Q8VDD5 Mouse
SwissProt: Q62812 Rat
Unigene: 474751 Human
Unigene: 29677 Mouse
Unigene: 11385 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.