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货号： bs-11143R-HRP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11143R-HRP
- 英文名称
- Anti-PCDHGA10/HRP
- 中文名称
- 辣根过氧化物酶标记的原钙粘蛋白γ10抗体
- 别 名
- PCDH gamma A10; PCDHGA 10; PCDHGA-10; Protocadherin gamma A10; PCDGA_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 信号转导 细胞粘附分子 细胞骨架 细胞外基质 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 98kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PCDHGA10
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGA10 (Protocadherin gamma-A10) is a 936 amino acid that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA10 is a member of the gamma subfamily A. PCDHGA10 is a type I transmembrane receptor containing six cadherin motifs and is expressed in the central nervous system where it localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGA10 that are produced as a result of alternative splicing events.
Function:
Potential calcium dependent cell adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Location:
Cell membrane; Single pass type I membrane protein.
Similarity:
Contains 6 cadherin domains.
Database links:Entrez Gene: 56106 Human
Omim: 606297 Human
SwissProt: Q9Y5H3 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.