概述| 货号 | RDC1823 |
| 别名 | CD309 antigen; CD309; EC 2.7.10; EC 2.7.10.1; Fetal liver kinase 1; fetal liver kinase-1; Flk1; Flk-1; FLK1tyrosine kinase growth factor receptor; KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; vascular endothelial growth factor receptor 2; VEGF R2; VEGFR; VEGFR2; VEGFR-2 |
全称 | Vascular Endothelial Growth Factor Receptor 2 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3791 (Human); 16542 (Mouse) |
| 背景 | VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Airway Inflammation and Remodeling
- Cancer Biomarkers
- Cytokine and Growth Factor Receptors on VSMC
- Endothelial Cell Differentiation Markers
- Endothelial Cell Markers
- Endothelial Progenitor and Endothelial Cell Markers
- Endothelial Progenitor Cell Markers
- Hemangioblasts
- Hematopoietic Stem Cell Markers
- HIF Transcription Factors
- Myeloid-derived Suppressor Cells (MDSC)
- Platelets
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- Receptors in the Jak/STAT Pathway
- Semaphorins, Plexin Receptors, and Related Molecules
- VEGF Family
- VEGF Receptors and Regulators on Endothelial Cells
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