Mouse Plexin B1 (NP 766363) VersaClone cDNA (10 UG)
货号：
RDC0720 基本售价：
11332.3 元 规格：
10 ug
产品信息
概述| 货号 | RDC0720 |
| 别名 | plexin B1; PLXN5; PLXNB1; SEP; Transmembrane Protein SEP |
| 反应种属 | Mouse |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5364 (Human); 235611 (Mouse); 316009 (Rat) |
| 背景 | Plexin B1 is a 300 kDa member of the B subfamily, Plexin family of Semaphorin receptors. Mature human Plexin B1 is a 2116 amino acid type I transmembrane (TM) glycoprotein that contains a 1471 aa extracellular domain (ECD) and a 612 aa cytoplasmic region. The ECD contains one Semaphorin domain, two PSI domains, and three IPT repeats. The ECD is cleaved into two subunits, a 200 kDa a-chain (aa 20-1305) and a 100 kDa TM b-chain. The subunits are nondisulfide-linked and generate a high-affinity receptor. Plexin B1 is a receptor for Semaphorin 4D/CD100. It forms a receptor complex with Neuropilins, MET, and EGF R2. Multiple splice variants are known. One shows a deletion of aa 689-871. A second shows a 53 aa substitution for aa 677-2135. And a third shows a 53 aa substitution for the 53 aa between aa 677-729. Over aa 35-150, human Plexin B1 is 90% and 97% aa identical to dog and mouse Plexin B1, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - ICC / IHC Images: Plexin B1
- Semaphorins, Plexin Receptors, and Related Molecules
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