概述| 货号 | RDC1267 |
| 别名 | EC 2.7.10; EC 2.7.10.1; FLT; FLT1; Flt-1; Fms-like tyrosine kinase 1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor); FRT; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; vascular endothelial growth factor receptor 1; Vascular permeability factor receptor; VEGFR1; VEGFR-1 |
全称 | Vascular Endothelial Growth Factor Receptor 1 | | 反应种属 | Mouse |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2321 (Human); 14254 (Mouse) |
| 背景 | VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Airway Inflammation and Remodeling
- Cancer Biomarkers
- Endothelial Cell Differentiation Markers
- Endothelial Cell Markers
- Endothelial Progenitor and Endothelial Cell Markers
- HIF Transcription Factors
- ICC / IHC Images: VEGF R1/Flt-1
- Mini-review: Vascular Endothelial Growth Factor (VEGF)
- Myeloid-derived Suppressor Cells (MDSC)
- Platelets
- Preeclampsia
- Proliferation Bioassay HUVECs
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- Receptors in the Jak/STAT Pathway
- Technical Notes: The Quantikine ELISA in Establishing a Role for Endoglin in Preeclampsia
- VEGF Family
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