概述| 货号 | RDC1061 |
| 别名 | c-erbB3; EC 2.7.10; EC 2.7.10.1; ErbB-3; erbB3-S; HER3; HER3c-erbB-3; LCCS2; lethal congenital contracture syndrome 2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; Proto-oncogene-like protein c-ErbB-3; receptor tyrosine-protein kinase erbB-3; Tyrosine kinase-type cell surface receptor HER3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
全称 | Receptor Tyrosine Protein Kinase ErbB3 | | 反应种属 | Mouse |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2065 (Human); 13867 (Mouse) |
| 背景 | ErbB3, also called Her3 (human epidermal growth factor receptor 3) in humans, is a type I transmembrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB3 binds neuregulins NRG1 and NRG2, but lacks a working kinase domain; heterodimerization with another ErbB receptor is required for signaling. ErbB3 is important in development of Schwann cells, neural crest cells, heart valves and the sympathetic nervous system. When expressed with ErbB2 in breast, skin, ovary and gastrointestinal tumors, ErbB3 is a potent mitogen. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cancer Biomarkers
- EGF Family
- ICC / IHC Images: ErbB3/Her3
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- The ErbB Family - Talk and Crosstalk
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