Human UNC5H2/UNC5B (NP_734465) VersaClone cDNA (10 UG)
货号：
RDC1777 基本售价：
7078.9 元 规格：
10 ug
产品信息
概述| 货号 | RDC1777 |
| 别名 | p53RDL1; p53-regulated receptor for death and life protein 1; Protein unc-5 homolog 2; Protein unc-5 homolog B; transmembrane receptor Unc5H2; unc5 (C.elegans homolog) b; unc-5 homolog 2; unc-5 homolog B (C. elegans); UNC5B; UNC5H2; UNC5H2netrin receptor UNC5B |
全称 | Netrin Receptor UNC5B |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 219699 (Human); 60630 (Rat) |
| 背景 | Members of the UNC5H family are best known as receptors for the axon guidance molecule netrin. Structurally, UNC5Hs have two Ig and two thrombospondin type 1 domains in their extracellular region, and a conserved ZU-5 domain, a deleted in colorectal cancer (DCC)-binding domain, and a C-terminal death domain in their cytoplasmic region. In general, they mediate the chemorepulsive effects of netrin, while the other netrin receptor subtype, DCC, mediates attraction. Members of the UNC5H family have also been implicated as tumor suppressors and regulators of apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Apoptosis
- Axon Guidance and Neuron Migration
- Netrins and Receptors
- Repulsive Guidance Molecules and Receptors
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