概述货号 | RDC1494 |
别名 | FGF R2 alpha; FGFR2a |
全称 | Fibroblast Growth Factor Receptor 2 alpha | 反应种属 | Mouse |
性能供应商 | R&D Systems |
Entrez Gene IDs | 2263 (Human); 14183 (Mouse) |
背景 | FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - FGF Family
- FGF Ligands
- FGF Regulators
- Fibroblast Growth Factor Superfamily
- Fibroblast Growth Factors and their Receptors
- Glial Lineage Markers
- Mini-review: Fibroblast Growth Factors (FGFs)
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- Receptors in the Jak/STAT Pathway
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