概述| 货号 | RDC0624 |
| 别名 | IL-17 receptor E; Il25r; interleukin 17 receptor E |
全称 | Interleukin 17 Receptor E | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 132014 (Human); 57890 (Mouse); 362417 (Rat) |
| 背景 | Interleukin-17 Receptor E (IL-17 RE) is a transmembrane protein that is expressed on mucosal epithelial cells, keratinocytes, Th17 cells, and gamma delta T cells. It associates with IL-17 RA to form a heterodimeric receptor for IL-17C. Binding of IL-17C to this receptor complex promotes mucosal immunity by stimulating the production of anti-bacterial peptides and pro-inflammatory cytokines and chemokines. Additionally, IL-17C signaling regulates Th17 cell-dependent immune responses and has been suggested to contribute to psoriatic skin thickening, the progression of arthritis, and the pathogenesis of autoimmune diseases. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | |
