概述| 货号 | RDC1453 |
| 别名 | signal transducer and activator of transcription 4; SLEB11 |
全称 | Signal Transducer and Activator of Transcription 4 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 6775 (Human); 20849 (Mouse) |
| 背景 | Signal transduction and activator of transcription 4 (STAT4) is a member of the Jak/STAT signal transduction pathway. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo or heterodimerizes with other STAT proteins, which then translocate to the nucleus and activate transcription of specific genes. STAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Apoptosis Transcription Factors and Regulators
- Hematopoietic Stem Cell Transcription Factors and Regulators
- IL-12 Family
- Immunoglobulin-Like Domain Transcription Factors
- Interactive Pathway: Th1 Differentiation
- Jak and STAT Proteins
- Mini-review: STAT Proteins
- STAT
- Th1 Cells
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