概述| 货号 | RDC0555 |
| 别名 | EC 2.7.10; EC 2.7.10.1; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; NT 3 receptor; NT-3 growth factor receptor; NTRK3; TrkC tyrosine kinase; trk-C; TRKCneurotrophin 3 receptor; tyrosine kinase receptor C |
全称 | Neurotrophic Tyrosine Kinase Receptor C | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 4916 (Human); 18213 (Mouse); 29613 (Rat) |
| 背景 | Members of the Tyrosine Kinase Receptor (Trk) family (TrkA, TrkB, and TrkC) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth. TrkC is predominantly expressed in the central nervous system. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - ICC / IHC Images: TrkC
- Mini-review: Neurotrophic Factors
- Neurotrophin/Trk Family
- Receptor Tyrosine Kinases (RTKs)
- Receptor Tyrosine Kinases (RTKs) in the Akt Pathway
- VPS10P-domain Family
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