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货号： bs-3577R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3577R-Cy7
- 英文名称
- Anti-DMT1/Cy7
- 中文名称
- Cy7标记的金属离子转运体1抗体
- 别 名
- DCT 1; DCT1; Divalent metal transporter 1; DMT 1; DMT1; Natural resistance associated macrophage protein 2; NRAMP 2; NRAMP2; NRAM2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 62kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DMT1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
DMT1 is a major transporter of ferrous iron from the intestinal lumen. DMT1 belongs to the family of NRAMP metal ion transporters which function in diverse organisms from bacteria to human. DMT1 (NRAMP2) transports metal ions at the plasma membrane of cells of both the duodenum and in peripheral tissues, and defective DMT1 causes anaemia.
Function:
Actin-bundling protein. May function in mitogen-activated protein kinase pathway.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Heart, brain, lung, skeletal muscle, and kidney.
Post-translational modifications:
Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase.
Similarity:
Belongs to the villin/gelsolin family.
Contains 1 HP (headpiece) domain.
Database links:Entrez Gene: 4891 Human
Entrez Gene: 18174 Mouse
Omim: 600523 Human
SwissProt: P49281 Human
SwissProt: P49282 Mouse
Unigene: 505545 Human
Unigene: 234608 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.