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货号： bs-4054R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4054R-Cy7
- 英文名称
- Anti-MAT2A/Cy7
- 中文名称
- Cy7标记的蛋氨酸腺苷转移酶抗体
- 别 名
- MAT2A AdoMet synthetase 2; AdoMet synthetase; AMS 2; AMS2; MAT 2A; MAT II; MATA 2; MATA2; MATII; Methionine adenosyltransferase 2; Methionine adenosyltransferase; Methionine adenosyltransferase II alpha; Methionine adenosyltransferase II; S adenosylmethionine synthetase gamma form; S adenosylmethionine synthetase isoform type 2; SAMS 2; SAMS2; METK1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Zebrafish, Monkey,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 44kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Methionine adenosyltransferase (31-80aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
S adenosylmethionine synthetase catalyzes the formation of S adenosylmethionine from methionine and ATP. In mammalian tissues, there are three distinct forms of AdoMet synthases designated as alpha, beta, and gamma. Alpha and beta are expressed only in adult liver, while gamma is widely distributed in extrahepatic tissues.
Function:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
Subunit:
Homotetramer (MAT-I) or homodimer (MAT-III).
Tissue Specificity:
Expressed in liver.
Post-translational modifications:
S-nitrosylation of Cys-120 inactivates the enzyme (By similarity).
DISEASE:
Defects in MAT1A are the cause of methionine adenosyltransferase deficiency (MATD) [MIM:250850]; also called MAT I/III deficiency. MATD is an inborn error of metabolism resulting in isolated hypermethioninemia. Most patients have no clinical abnormalities, although some neurologic symptoms may be present in rare cases with severe loss of methionine adenosyltransferase activity.
Similarity:
Belongs to the AdoMet synthase family.
Database links:Entrez Gene: 459363Chimpanzee
Entrez Gene: 101865874 Cynomolgus Monkey
Entrez Gene: 475770Dog
Entrez Gene: 4144Human
Entrez Gene: 232087Mouse
Entrez Gene: 171347Rat
Entrez Gene: 695362 Rhesus monkey
Entrez Gene: 323329Zebrafish
Omim: 601468Human
SwissProt: Q4R924 Cynomolgus Monkey
SwissProt: P31153Human
SwissProt: Q3THS6Mouse
SwissProt: Q5R5H1Orangutan
SwissProt: P18298Rat
Unigene: 516157Human
Unigene: 29815Mouse
Unigene: 485037Mouse
Unigene: 144658Rat
Unigene: 41420Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.