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货号: bs-4058R-Cy7 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-4058R-Cy7
- 英文名称
- Anti-EHHADH/Cy7
- 中文名称
- Cy7标记的三羟酰辅酶A脱氢酶抗体
- 别 名
- 3 hydroxyacyl CoA dehydrogenase; 3,2 trans enoyl CoA isomerase; ECHD antibody Enoyl Coenzyme A, hydratase/3 hydroxyacyl Coenzyme A dehydrogenase; L 3 hydroxyacyl CoA dehydrogenase; L bifunctional protein, peroxisomal; L PBE; LBFP; LBP; MGC120586; PBE; PBFE; Peroxisomal bifunctional enzyme; Peroxisomal enoyl CoA hydratase.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 79kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EHHADH
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
EHHADH is one of three preoxisomal enzymes of the classic peroxisomal Beta-oxidation cycle involved in the catabolism of free fatty acids.Most dietary long chain fatty acids are oxidized in the mitochondria, but very-long-chain fatty acids (VLCFAs) must be shortened first by peroxisomal Beta-oxidation prior to complete oxidation in mitochondria.
Subunit:
Monomer.
Subcellular Location:
Peroxisome.
Tissue Specificity:
Liver and kidney. Lower amounts seen in the brain.
Post-translational modifications:
Acetylated, leading to enhanced enzyme activity. Acetylation is enhanced by up to 80% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with highest increase on Lys-346. Acetylation and enzyme activity increased by about 1.5% on addition of fatty acids.
Similarity:
In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Database links:Entrez Gene: 1962 Human
Entrez Gene: 74147 Mouse
Omim: 607037 Human
SwissProt: Q08426 Human
SwissProt: Q9DBM2 Mouse
Unigene: 429879 Human
Unigene: 28100 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.