产品中心
当前位置：首页>产品中心Anti-Ceramide synthase 2/Cy7
货号： bs-5077R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5077R-Cy7
- 英文名称
- Anti-Ceramide synthase 2/Cy7
- 中文名称
- Cy7标记的肿瘤转移抑制基因1抗体
- 别 名
- LASS2; TMSG-1; CerS 2; CerS2; L3 antibody LAG1 homolog ceramide synthase 2; LAG1 longevity assurance 2; LAG1 longevity assurance homolog 2; LASS 2; Longevity assurance (LAG1 S. cerevisiae) homolog 2; TMSG 1; TMSG1; Tumor metastasis suppressor; Tumor metastasis suppressor gene 1 protein; FLJ10243; MGC987; SP 260; SP260.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LASS2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
Function:
Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.
Subcellular Location:
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in kidney, liver, brain, heart, placenta and lung
Similarity:
Contains 1 homeobox DNA-binding domain.
Contains 1 TLC (TRAM/LAG1/CLN8) domain.
Database links:Entrez Gene: 29956Human
Entrez Gene: 76893Mouse
Omim: 606920Human
SwissProt: Q96G23Human
SwissProt: Q924Z4Mouse
Unigene: 713103Human
Unigene: 741232Human
Unigene: 181009Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.