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货号： bs-3839R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-3839R-Cy7
- 英文名称
- Anti-eI4EBP2/Cy7
- 中文名称
- Cy7标记的eIF4E结合蛋白2抗体
- 别 名
- Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.Full=Eukaryotic translation initiation factor 4E-binding protein 2; 4E-BP2; eIF4E-binding protein 2; 4EBP2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 染色质和核信号 信号转导 细胞凋亡 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 17/20kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human 4E-BP2
- 亚 型
- IgG
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- 0
- 产品介绍
- background:
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]
Function:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway.
Subunit:
Nonphosphorylated EIF4EBP2 interacts with EIF4E.
Post-translational modifications:
Phosphorylated on serine and threonine residues in response to insulin, EGF and PDGF.
Similarity:
Belongs to the eIF4E-binding protein family.
Database links:Entrez Gene: 1979 Human
Entrez Gene: 13688 Mouse
Entrez Gene: 361845 Rat
Omim: 602224 Human
SwissProt: Q13542 Human
SwissProt: P70445 Mouse
Unigene: 621200 Human
Unigene: 730236 Human
Unigene: 259516 Mouse
Unigene: 24129 Rat