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货号： bs-5149R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5149R-Cy7
- 英文名称
- Anti-CPI17 alpha/Cy7
- 中文名称
- Cy7标记的蛋白磷酸激酶PKC/CPI-17抗体
- 别 名
- 17kDa PKC potentiated inhibitory protein of PP1; CPI 17 alpha; CPI 17; CPI 17alpha; CPI17; CPI-17; PKC potentiated inhibitory protein of PP1; PPP1INL; PPP1R14A; Protein phosphatase 1; Protein phosphatase 1 regulatory (inhibitor) subunit 14A; Protein phosphatase 1 regulatory subunit 14A; Regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; 17-KDa protein; 17kDa PKC potentiated inhibitory protein of PP1; PKC potentiated inhibitory protein of PP1; PKC potentiated inhibitory protein of PP1, 17-KD; PP14A_HUMAN; Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD; Protein kinase C-potentiated inhibitor protein of 17 kDa; Protein phosphatase 1; Protein phosphatase 1 regulatory (inhibitor) subunit 14A; Regulatory subunit 14A.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 信号转导 转录调节因子 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Pig, Cow, Rabbit, Sheep,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 17kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CPI17 alpha
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]
Function:
nhibitor of PPP1CA. Has over 1000-fold higherinhibitory activity when phosphorylated, creating a molecularswitch for regulating the phosphorylation status of PPP1CAsubstrates and smooth muscle contraction.
Subcellular Location:
Cytoplasm
Tissue Specificity:
Isoform 1 is detected in aorta and testis.Isoform 2 is detected in aorta.
Similarity:
Belongs to the PP1 inhibitor family.
Database links:Entrez Gene: 94274Human
Entrez Gene: 68458Mouse
Entrez Gene: 114004Rat
Omim: 608153Human
SwissProt: Q96A00Human
SwissProt: Q91VC7Mouse
SwissProt: Q99MC0Rat
Unigene: 631569Human
Unigene: 2343Mouse
Unigene: 73852Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.