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货号： bs-5159R-Cy7 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5159R-Cy7
- 英文名称
- Anti-MYLPF/Cy7
- 中文名称
- Cy7标记的快速骨骼肌肌球蛋白轻链2抗体
- 别 名
- 2410014J02Rik; DKFZp779C0757; DTNB; Fast skeletal myosin light chain 2; G2; HUMMLC2B; MGC13450; MLC 2; MRLC2; MYL11; MLC2B; MLC2F; MLRS_HUMAN; MYLPF; Myosin light polypeptide 2 alkali; Myosin regulatory light chain 2, skeletal muscle isoform.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 信号转导 细胞骨架 细胞外基质
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 19kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Fast skeletal myosin light chain 2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins, striated muscle Myosins and non-muscle Myosins . Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.
Subunit:
Myosin is a hexamer of 2 heavy chains and 4 light chains.
Tissue Specificity:
Expressed in fetal and adult skeletal muscle.
Similarity:
Contains 3 EF-hand domains.
Database links:Entrez Gene: 29895Human
Entrez Gene: 396470Chicken
Entrez Gene: 317657Cow
Entrez Gene: 4632Human
Entrez Gene: 17901Mouse
Entrez Gene: 17907Mouse
Entrez Gene: 24584Rat
Entrez Gene: 56781Rat
Omim: 160780Human
SwissProt: P02609Chicken
SwissProt: P05976Human
SwissProt: P06741Human
SwissProt: Q14324Human
SwissProt: P05978Mouse
SwissProt: P97457Mouse
SwissProt: P02602Rabbit
SwissProt: P02603Rabbit
SwissProt: P02600Rat
SwissProt: P04466Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.